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No. of pages: 46

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Abstract:

Several plants have been used in the treatment of various disorders without a scientific basis. The present study examines the pancreatic effect of Buchholzia coriacea formulated diet in sucrose-fed pregnant rats and their offspring. Buchholzia coriacea seeds were obtained from Ogbete main market, Enugu state, identified, dried, and grounded using a miller machine. 10% of the seed powder was used to formulate their diet.
Thirty (240) adult female and six (6) adult male albino rats (180-250 g) were used in this study. High sucrose (20%) was given via drinking water to animals before, during, and after pregnancy. Group A; Control normal was administered distilled water, group B received sucrose + 10% Buchholzia Coriacea formulated diet (BCFD), Group C; untreated rats were administered sucrose and distilled water while Group D received 10% Buchhoiza Coriacea formulated diet (BCFD) only.
All animals were sacrificed following an overnight fast by anesthetic does to diethylether and cervical dislocation. Blood samples were obtained through cardiac puncture error of the mean. SUC (20%) (untreated) significantly elevated blood glucose levels (P