Fill the blank spaces with the most appropriate of options A-E:
In the past 20 years, many patients .... by the doctors in the specialist hospital.
The time marker “in the past 20 years” suggests something that started in the past and continues up to the present. That requires the Present Perfect tense (have/has + past participle).
The subject is “many patients”, not the doctors. So we need a passive construction: have been + past participle.
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