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Chemical breakdown of large food molecules into smaller and soluble substances is the function of 

Biology
JAMB 2025

Chemical breakdown of large food molecules into smaller and soluble substances is the function of 

  • A. large intestine
  • B. duodenum
  • C. rectum
  • D. ileum
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Correct Answer: Option B
Explanation

The duodenum is the first section of the small intestine and the primary site where chemical digestion is completed. In this region, chyme from the stomach mixes with bile from the liver and digestive enzymes from the pancreas. These enzymes (such as amylase, trypsin, and lipase) catalyze the chemical breakdown of large, complex molecules—carbohydrates, proteins, and fats—into smaller, soluble substances like glucose, amino acids, and fatty acids that the body can absorb. 

A. Large intestine: Its primary function is the absorption of water and electrolytes, not the chemical breakdown of food molecules. While bacteria in the colon perform some fermentation, it is not the main site for the initial chemical breakdown of food into soluble nutrients.

C. Rectum: The rectum serves as a temporary storage site for feces (undigested waste) before they are eliminated from the body through the anus. No significant digestion occurs here.

D. Ileum: The ileum is the final section of the small intestine. While some digestion may continue, its principal role is the absorption of vitamin B12, bile salts, and any remaining nutrients that were not absorbed in the earlier sections of the small intestine.

There is an explanation video available below.


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Explanation Video

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