donor and the recipient belong to the same blood group
same antibodies from donor and recipient fuse together
donor and the recipient belong to different race
recipient is not a universal recipient
antigens and anitbody in the donor and the recipient react
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There are two antigens A and B found on the surface of the red blood cell. There are two antibodies anti-A and anti-B found on the plasma. Each individual have a contracting antibody to avoid clumping of blood or agglutination . Hence during blood transfusion of wrong blood group the antibodies react with the incorrect transfused blood group as a result of the erthrocytes clumped up and stick together causing them to agglutinate that is why the antigen and antibodies in the receipt and donor react
