you have 500 barrels full of water,one of which is poisoned. You have a number...

you have 500 barrels full of water,one of which is poisoned. You have a number of test mice and you want know the number of the poisoned barrels using least number of mice. One drop of poisoned water is enough to kill a mouse. The effect of the poison kill the mouse within 24hr. It is required to determined the number of the poisoned barrel if you have 2 days(48 hours) to conduct the experiment to determines the barrel number?

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